2.3.1.220 | 3 malonyl-CoA + benzoyl-CoA = 4 CoA + 2,4,6-trihydroxybenzophenone + 3 CO2 |
the enzyme catalyzes the iterative condensation of benzoyl-CoA with three molecules of malonyl-CoA to give a linear tetraketide intermediate, which is subsequently cyclized into 2,4,6-trihydroxybenzophenone via intramolecular Claisen condensation, catalytic mechanism, overview |
704562 |