EC Number   |
Reaction |
Reference |
|---|
    2.1.2.1 | 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine |
enzyme exhibits threonine aldolase activity (EC 4.1.2.5), but the two enzymes are distinct |
441434 |
| 2.1.2.1 | 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine |
evidence for a direct transfer mechanism for the enzyme catalysed reaction |
441431 |
| 2.1.2.1 | 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine |
general mechanism of pyridoxal 5'-phosphate-catalyzed aldolic cleavage, racemisation, and transamination reactions, and catalytic mechanism of the transaldimination reaction involving Tyr55, His228, and Arg235, overview. Tyr55 is contributed by the symmetry-related monomer, with respect to the pyridoxal 5'-phosphate-binding subunit, and functions as the general acid-base catalyst in this proton transfer |
718984 |
| 2.1.2.1 | 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine |
mechanism |
-, 441402, 441403, 441404, 441405, 441407, 441412, 441415, 441416, 441417, 441418, 441419, 441420, 441424, 441430, 441432, 441434, 441436 |
| 2.1.2.1 | 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine |
stereochemistry |
441417, 441419, 441420 |
