EC Number |
Reaction |
Reference |
---|
2.1.1.72 | S-adenosyl-L-methionine + adenine in DNA = S-adenosyl-L-homocysteine + N6-methyladenine in DNA |
- |
- |
2.1.1.72 | S-adenosyl-L-methionine + adenine in DNA = S-adenosyl-L-homocysteine + N6-methyladenine in DNA |
active site structure, enzyme-methyl donor product interactions, substrate binding mechanism and conformational changes, overview |
659989 |
2.1.1.72 | S-adenosyl-L-methionine + adenine in DNA = S-adenosyl-L-homocysteine + N6-methyladenine in DNA |
D181 and Y184 are essential for activity |
659715 |
2.1.1.72 | S-adenosyl-L-methionine + adenine in DNA = S-adenosyl-L-homocysteine + N6-methyladenine in DNA |
molecular mechanism, effector action of substrates, progressive methylation of extended DNA containing more than one methylation site |
659905 |
2.1.1.72 | S-adenosyl-L-methionine + adenine in DNA = S-adenosyl-L-homocysteine + N6-methyladenine in DNA |
ordered bi bi mechanism during progressive methylation process |
659301 |
2.1.1.72 | S-adenosyl-L-methionine + adenine in DNA = S-adenosyl-L-homocysteine + N6-methyladenine in DNA |
ordered bi bi mechanism with S-adenosyl-L-homocysteine leaving at last, cooperative binding of 2 molecules of enzyme per DNA is required for activity |
659303 |
2.1.1.72 | S-adenosyl-L-methionine + adenine in DNA = S-adenosyl-L-homocysteine + N6-methyladenine in DNA |
ordered bi bi mechanism with S-adenosyl-L-methionine binding first, fast methyl transfer, slow product release |
659422 |
2.1.1.72 | S-adenosyl-L-methionine + adenine in DNA = S-adenosyl-L-homocysteine + N6-methyladenine in DNA |
reaction scheme and random bi bi kinetic mechanism |
659200 |
2.1.1.72 | S-adenosyl-L-methionine + adenine in DNA = S-adenosyl-L-homocysteine + N6-methyladenine in DNA |
steady-state-ordered bi-bi mechanism in which the order of substrate binding and product release is S-adenosyl-L-methionine, DNA, DNAMe, S-adenosyl-L-homocysteine |
485569 |
2.1.1.72 | S-adenosyl-L-methionine + adenine in DNA = S-adenosyl-L-homocysteine + N6-methyladenine in DNA |
two distinct stages of methylation under single turnover conditions |
659268 |