EC Number   |
Reaction |
Reference |
|---|
    2.1.1.37 | S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine |
catalytic reaction mechanism |
702450 |
| 2.1.1.37 | S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine |
catalytic reaction mechanism of Dnmt1, allosteric regulation with fast equilibrium, and substrate specificity. Base-flipping and base-stacking are the key mechanism in control of enzymatic activity, detailed overview |
703330 |
| 2.1.1.37 | S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine |
catalytic reaction mechanism of Dnmt1, overview |
703228 |
| 2.1.1.37 | S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine |
random sequential mechanism |
485287 |
| 2.1.1.37 | S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine |
sequential mechanism |
485304 |
| 2.1.1.37 | S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine |
sequential ordered bi-bi kinetic mechanism in which DNA binds to the enzyme first, followed by S-adenosyl-L-homocysteine and methylated DNA are released, formation of an enzyme-DNA-DNA ternary complex |
485302 |
| 2.1.1.37 | S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine |
the TSM biosensor method to study the interaction of M.SsoII with a 60 bp double-stranded DNA immobilized on the surface of a thickness shear mode (TSM) acoustic transducer. M.SsoII demonstrates a strong binding with any DNA duplex immobilized on the TSM transducer surface |
718577 |
