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Results 1 - 5 of 5
EC Number Reaction Commentary Reference
Show all pathways known for 1.7.1.7Display the word mapDisplay the reaction diagram Show all sequences 1.7.1.7IMP + NH3 + NADP+ = GMP + NADPH + H+ catalytic reaction mechanism, overview. GMPR catalyzes two different chemical transformations at the same active site via two different cofactor conformations, analysis by subtesla high resolution field cycling NMR relaxometry 742897
Show all pathways known for 1.7.1.7Display the word mapDisplay the reaction diagram Show all sequences 1.7.1.7IMP + NH3 + NADP+ = GMP + NADPH + H+ first order reaction 394290
Show all pathways known for 1.7.1.7Display the word mapDisplay the reaction diagram Show all sequences 1.7.1.7IMP + NH3 + NADP+ = GMP + NADPH + H+ mechanism: ordered sequential with GMP binding first 394287
Show all pathways known for 1.7.1.7Display the word mapDisplay the reaction diagram Show all sequences 1.7.1.7IMP + NH3 + NADP+ = GMP + NADPH + H+ ordered bi-bi kinetic mechanism, in which GMP binds first to the enzyme followed by NADPH binding, and NADP+ dissociates first followed by IMP release. GMP and IMP binding are thermodynamically favorable processes. Hydride transfer contributes to the rate-limiting step, and protonation and hydride transfer steps take place in the same transition state, lending support to a concerted mechanism. Product release does not contribute to the rate-limiting step of the reaction 725943
Show all pathways known for 1.7.1.7Display the word mapDisplay the reaction diagram Show all sequences 1.7.1.7IMP + NH3 + NADP+ = GMP + NADPH + H+ ordered bi–bi kinetic mechanism, in which GMP binds first to the enzyme followed by NADPH binding, and NADP+ dissociates first followed by IMP release 725943
Results 1 - 5 of 5