EC Number   |
Reaction |
Reference |
|---|
    1.14.14.9 | 4-hydroxyphenylacetate + FADH2 + O2 = 3,4-dihydroxyphenylacetate + FAD + H2O |
- |
- |
| 1.14.14.9 | 4-hydroxyphenylacetate + FADH2 + O2 = 3,4-dihydroxyphenylacetate + FAD + H2O |
catalytic mechanism and structure-function relationship, overview |
689748 |
| 1.14.14.9 | 4-hydroxyphenylacetate + FADH2 + O2 = 3,4-dihydroxyphenylacetate + FAD + H2O |
dehydration of the C4a-hydroxyflavin is the rate-determining step in catalysis |
438901 |
| 1.14.14.9 | 4-hydroxyphenylacetate + FADH2 + O2 = 3,4-dihydroxyphenylacetate + FAD + H2O |
different from other hydroxylases. Two-protein component enzyme: component C1 is a flavoprotein and C2 the hydroxylase component. Mechanism: 4-hydroxyphenylacetate binds to C1, then the enzyme-bound flavin is reduced by NADH, this reduced flavin is transferred to C2 and the reoxidation of the flavin occurs concurrently with the hydroxylation of the substrate |
438900 |
| 1.14.14.9 | 4-hydroxyphenylacetate + FADH2 + O2 = 3,4-dihydroxyphenylacetate + FAD + H2O |
enzymes of 4-hydroxyphenylacetic acid meta-cleavage pathway are sythesized following at least two sequential inductive events |
-, 438890, 438892 |
| 1.14.14.9 | 4-hydroxyphenylacetate + FADH2 + O2 = 3,4-dihydroxyphenylacetate + FAD + H2O |
family of external flavoprotein monooxygenases. The activity is induced by the substrates |
438895 |
| 1.14.14.9 | 4-hydroxyphenylacetate + FADH2 + O2 = 3,4-dihydroxyphenylacetate + FAD + H2O |
genes encoding the first four enzymes of the 4-hydroxyphenylacetic acid meta-pathway exist as two operons, one containing the hydroxylase gene while the other contains the other three |
438892 |
| 1.14.14.9 | 4-hydroxyphenylacetate + FADH2 + O2 = 3,4-dihydroxyphenylacetate + FAD + H2O |
kinetic mechanism of enzyme components C1 and C2 |
685182 |
| 1.14.14.9 | 4-hydroxyphenylacetate + FADH2 + O2 = 3,4-dihydroxyphenylacetate + FAD + H2O |
kinetic reaction mechanism, overview |
712503 |
| 1.14.14.9 | 4-hydroxyphenylacetate + FADH2 + O2 = 3,4-dihydroxyphenylacetate + FAD + H2O |
kinetic reaction mechanisms of the smaller FMN reductase enzyme component C1 and the larger oxygenase enzyme component C2, C2 shows a random order kinetic mechanism, detailed overview |
674577 |
