EC Number |
Reaction |
Reference |
---|
1.1.99.30 | a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor |
- |
- |
1.1.99.30 | a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor |
aldonates and aldarates with an (R)-configured alpha-carbon atom are converted to the corresponding 2-oxocarboxylates |
654958 |
1.1.99.30 | a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor |
Contains [4Fe-4S] and a mononucleotide molybdenum (pyranopterin) cofactor. Has broad substrate specificity, with 2-oxo-monocarboxylates and 2-oxo-dicarboxylates acting as substrates. Branching in a substrate at the C-3 position results in loss of activity. The enzyme from Proteus sp. is inactivated by oxygen |
- |
1.1.99.30 | a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor |
mechanism |
655713 |