EC Number   |
Reaction  |
Reference |
|---|
    4.3.2.2 | (S)-2-[5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide |
- |
- |
| 4.3.2.2 | (S)-2-[5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide |
kinetic and catalytic uni-bi rapid equilibrium ordered mechanism, key role for the conserved Ser298 in catalysis and pivotal role of the substrate in the activation of the catalytic base, detailed overview |
691116 |
| 4.3.2.2 | (S)-2-[5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide |
uni-bi mechanism, where fumarate is removed by beta-elimination via a general base-general acid mechanism |
695003 |
| 4.3.2.2 | N6-(1,2-dicarboxyethyl)AMP = fumarate + AMP |
kinetic and catalytic mechanism, the enzyme follows a rapid equilibrium ordered bi-uni mechanism in the reverse direction in which AMP binds first to the enzyme followed by fumarate, key role for the conserved Ser298 in catalysis and pivotal role of the substrate in the activation of the catalytic base, detailed overview |
691116 |
| 4.3.2.2 | N6-(1,2-dicarboxyethyl)AMP = fumarate + AMP |
uni bi-ordered mechanism |
34451 |
| 4.3.2.2 | N6-(1,2-dicarboxyethyl)AMP = fumarate + AMP |
uni-bi mechanism, where fumarate is removed by beta-elimination via a general base-general acid mechanism |
695003 |
