Refine search

Search Reaction

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 2 of 2
EC Number
Reaction
Commentary
Reference
(2E,6E)-farnesyl diphosphate = (+)-germacrene D + diphosphate
-
(2E,6E)-farnesyl diphosphate = (+)-germacrene D + diphosphate
the initial step is abstraction of the diphosphate moiety under ring closure to yield germacrenyl cation. The next step is a 1,2-hydride shift of H-7 into the isopropyl group, generating a germacrenyl cation with the positive charge at position 7. The cation undergoes a 1,2-hydride shift of H-6 yielding a cation with positive charge at position 6. During this step the configuration at C-7 is fixed. Finally, the cation is deprotonated at C-15 and the positive charge is quenched by two electron pair shifts to generate (+)-germacrene D
Results 1 - 2 of 2