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Results 1 - 4 of 4
EC Number
Reaction
Commentary
Reference
chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate
association of PabA and PabB is greatly enhanced by 5 mM glutamine and greatly reduced at cold temperatures; the enzyme is composed of two parts, PabA and PabB
chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate
in the absence of PabA and glutamine, PabB converts ammonia and chorismate into 4-amino-4-deoxychorismate (in the presence of Mg2+); non linear production of PABA in the ADC synthase-ADC lyase-coupled reaction system, at different glutamine and chorismate concentrations, with limiting PabB; the enzyme is composed of two parts, PabA and PabB
chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate
mechanism includes nucleophile addition to C2 of chorismate in an SN2'' process
chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate
omega-amino group of K274 adds to chorismate at C2, leading to elimination of the C4 hydroxyl in an SN2'' displacement reaction. After attack of ammonia to intermediate, another SN2'' displacement expels K274 and forms aminodeoxychorismate
Results 1 - 4 of 4