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EC Number Reaction Commentary Reference
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.270a 3beta-hydroxysteroid + NADP+ = a 3-oxosteroid + NADPH + H+ also acts on 5alpha-cholest-7-en-3-one -
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.270a 3beta-hydroxysteroid + NADP+ = a 3-oxosteroid + NADPH + H+ residues Leu/Val54, Tyr55, His117, Val128, Ile129, His222, and Trp227 are involved in substrate binding, Tyr55, Asp50, Lys84, and His117 form the catalytic tetrad, Tyr55 and His117 together with NADP+ form an oxyanion hole through hydrogen bond networks, molecular docking simulations, detailed overview 677144
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.270a 3beta-hydroxysteroid + NADP+ = a 3-oxosteroid + NADPH + H+ stereoselectivity : #1,4,5# catalyzes reduction of the 3-keto group to a 3beta-hydroxyl group <5,6,7> 286474, 286477
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