EC Number   |
Posttranslational Modification |
Reference |
|---|
   3.4.24.34 | glycoprotein |
- |
31209 |
| 3.4.24.34 | glycoprotein |
MMP-8 is secreted as glycosylated zymogen, with a prodomain bound to the metal active site |
755297 |
| 3.4.24.34 | proteolytic modification |
MMP-8 is secreted as glycosylated zymogen, with a prodomain bound to the metal active site. Catalysis is activated by proteolytic cleavage of the prodomain, which exposes the active site |
755297 |
| 3.4.24.34 | proteolytic modification |
pro-MMP-8 is activated by trypsin cleavage |
-, 754245 |
| 3.4.24.34 | proteolytic modification |
recombinant mutant enzymes are purified in the proenzyme form and all display an apparent molecular mass of 79000 Da, 4-aminophenylmercuric acetate-initiated autolytic processing to the fully activated form of the purified mutants, generation of the 59000 Da active enzyme after removal of the propeptide |
669348 |
| 3.4.24.34 | proteolytic modification |
the pro-MMP-8 is processed to its active form |
683989 |
