EC Number   |
Posttranslational Modification |
Reference |
|---|
   3.4.21.34 | glycoprotein |
- |
650493, 683199, 732931, 752857, 95372 |
| 3.4.21.34 | proteolytic modification |
prekallikrein is activated by factor XIIa |
684080 |
| 3.4.21.34 | proteolytic modification |
prekallikrein is synthesized in hepatocytes and other cell types and secreted to the blood, and proteolytically activated to kallikrein |
683208 |
| 3.4.21.34 | proteolytic modification |
the plasma kallikrein/kinin system has two mechanisms for its activation: one that is dependent and another independent of factor XII, the latter is realized by autoactivation on a negatively charged artificial or biologic surface or by serine protease prolylcarboxypeptidase, a PK activator on endothelial cell surfaces, while factor XIIa performs proteolytic activation of the zymogen prekallikrein, overview |
683546 |
