EC Number   |
Posttranslational Modification |
Reference |
|---|
   3.1.1.53 | glycoprotein |
- |
673893, 750712 |
| 3.1.1.53 | glycoprotein |
glycosylation influences the biological activity of the enzyme and is essential for release of the enzyme into the culture medium |
750708 |
| 3.1.1.53 | glycoprotein |
N-glycosylation sites: N107, N138, N267, N290, N401, N422. O-glycosylation sites: S177, S231, S242, T511 |
750708 |
| 3.1.1.53 | glycoprotein |
purified, recombinant protein, deglycosylation with N-glycosidase F |
701059 |
| 3.1.1.53 | phosphoprotein |
phosphorylation sites: S30, Y31, T52, S74, S79, S144, S156, S158, S217, T221, S227, S228, S247, S255, T303, S308, T312, S328, S331, S332, Y349, S371, T461, S470 |
750708 |
| 3.1.1.53 | proteolytic modification |
sequence contains a strong putative N-terminal secretion signal with a potential cleavage site after alanine 18 |
749847 |
| 3.1.1.53 | proteolytic modification |
the 58000 kDa form of SIAE is rapidly proteolitically cleaved to a 49000 Da form or glycosylated to the 62000 Da form |
750708 |
| 3.1.1.53 | side-chain modification |
- |
94415 |
| 3.1.1.53 | side-chain modification |
contains N-linked oligosaccarides, after treatment with peptide N-glycosidase decrease of 10000 Da in the apparent molecular weight, endoglycosidase H causes a much smaller shift |
94417 |
| 3.1.1.53 | side-chain modification |
glycoprotein, linked with N-oligosaccharides, LSE, cleaved by endo-beta-N-acetylglycosaminidase H and peptide:N-glycosidase F |
94416, 94417 |
