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EC Number Posttranslational Modification Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.7.4.21phosphoprotein the phosphorylation of IP6K1 at a PKC/PKA motif modulates its interaction with PLIN1 and lipolysis. GST-IP6K1 phosphorylation in HEK293 cells is enhanced by forskolin-mediated PKA activation. Endogenous IP6K1 phosphorylation in HEK293 cells is enhanced to a greater extent by PKC activation compared to PKA activation as evidenced by PMA and FSK treatments. No phosphorylation of IP6K1 mutant S118A-S121A in HEK293 cells 738392
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