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EC Number	Posttranslational Modification	Commentary	Reference
1.3.1.72	more	DHCR24 is also regulated post-translationally, overview	746354
1.3.1.72	more	enzyme possesses a potential N-terminal secretory signal	654165
1.3.1.72	phosphoprotein	protein kinase C (PKC) activates DHCR24 activity through reversible phosphorylation. PKC inhibitors, BIM and Ro-318220, reduce cholesterol levels and accumulate desmosterol within 4 h, indicating decreased DHCR24 activity. Phosphorylation at T110 modulates DHCR24 activity	745512

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Release 2023.1 (January 2023)