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Posttranslational Modification
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1.14.15.15
proteolytic modification
the naturally occuring truncated enzyme form is formed by via proteolytic processing of CYP27A by endogenous protease
671685
1.14.15.15
side-chain modification
treatment of enzyme with iso[4]levuglandin E2 in vitro diminishes enzyme activity. Lys residues Lys134, Lys358, and Lys476, readily interact iso[4]levuglandin E2 in vitro, and modified CYP27A1 is present in the retina
725428
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