EC Number   |
Posttranslational Modification |
Reference  |
|---|
   2.7.11.16 | phosphoprotein |
major autophosphorylation sites are Ser484 and Thr485 |
491154 |
| 2.7.11.16 | lipoprotein |
palmitoylation of GRK6 appears essential for membrane association |
491155 |
| 2.7.11.16 | more |
mechanisms of regulation of GRK protein stability and degradation, e.g. via ubiquitination or protease cleavage, overview |
661455 |
| 2.7.11.16 | phosphoprotein |
GRK5 performs autophosphorylation and is phosphorylated by protein kinase C |
661455 |
| 2.7.11.16 | lipoprotein |
the C-terminus of GRK6 is palmitoylated, not required for phosphorylation activity |
661709 |
| 2.7.11.16 | lipoprotein |
GRK4-6 are permanently modulated by fatty acids and/or phospholipids |
662911 |
| 2.7.11.16 | phosphoprotein |
regulation of GRK5 by phosphorylation through PKC, GRK5 is activated by autophosphorylation, autophosphorylation is stimulated by phospholipids, such as phosphatidylinositol-4,5-bisphosphate, overview |
662911 |
| 2.7.11.16 | lipoprotein |
GRK4 is palmitoylated at the C-terminus |
662921 |
| 2.7.11.16 | phosphoprotein |
phosphorylation, e.g. by PKA, PKC, ERK1/2 or c-SRC, activates the enzyme |
672408 |
| 2.7.11.16 | lipoprotein |
GRK6 is palmitoylated at Cys561, Cys562, and Cys565 |
674574 |
