EC Number   |
Application |
Reference |
|---|
   3.4.24.74 | medicine |
among stool strains from colon cancer patients, bft-1 is found to be more common than bft-2, isoform bft-1 is also found in almost all isolates from extraintestinal sites, strain NCTC 11295 harbours the isoform bft-2 |
-, 667180 |
| 3.4.24.74 | medicine |
oral administration with lower-dose biologically active recombinant isoform BFT-2 inhibits colorectal tumorigenesis in mice |
755658 |
| 3.4.24.74 | medicine |
stimulates interleukin-8 secretion by human intestinal epithelial HT29/C1 cells, biological active BFT, but not serum, is required for interleukin-8 production, NF-kB, tyrosine kinase and mitogen activated protein kinase signaling pathways are involved in BFT-induced interleukin-8 stimulation |
-, 668909 |
| 3.4.24.74 | more |
intestinal epithelial cells in vitro possess a specific membrane BFT receptor that is distinct from E-cadherin |
-, 668931 |
| 3.4.24.74 | more |
single point mutations in the zinc-binding metalloprotease motif do not affect BFT processing but do reduce or eliminate BFT biologic activity in vitro |
668924 |
