Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Application

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 8 of 8
EC Number Application Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.68medicine causative agent of the disease tetanus 652905
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.68medicine HuscFv antibodies specific for heavy chain can protect against tetanus neurotoxin by inhibiting binding of the enzyme to ganglioside GT1b 754805
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.68medicine monoclonal antibody MAb 5C4 is the only anti-fragment C (heavy chain) antibody which is capable of blocking the binding of recombinant fragment C to GT1b gangliosides 754911
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.68medicine sole causal agent of the pathological condition known as tetanus 649097
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.68medicine sole cause of the devastating disease tetanus 650578
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.68medicine the antibodies 2-7G, 2-2D, and S-4-7H can effectively inhibit the binding between the heavy chain fragment of the enzyme (TeNT-Hc) and differentiated PC-12 cells in vitro. Moreover, 2-7G inhibits TeNT-Hc binding to the receptor via carbohydrate-binding sites of the W pocket while 2-2D and S-4-7H inhibit binding of the R pocket. Although no single antibody completely protect mice from the toxin, they can prolong survival 755610
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.68medicine treatment of T cells with recombinant carboxy-subdomain of the heavy chain results in development of Th1 lineage phenotype, which might lead to a specific and protective antibody mediated response against the enzyme 753215
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.68medicine very powerful neurotoxin, agent responsible for all clinical symptoms of tetanus -, 653717
Results 1 - 8 of 8