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Results 1 - 9 of 9
EC Number Application Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.49diagnostics measurement of separase proteolytic activity in single living cells by a fluorogenic flow cytometry assay. The assay is used to quantify Separase proteolytic activity in leukemic cell lines and peripheral blood samples from leukemia patients 755097
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.49medicine due to the oncogenic activity of cohesin protease, separase in human cancer cells, modulation of separase enzymatic activity could constitute a new therapeutic strategy for targeting resistant, separase-overexpressing aneuploid tumors 752988
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.49medicine the results show that separase might be a tumor supressor gene 680013
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.49molecular biology data suggest that the co-ordinated expression of separase, securin and Rad21 is fundamental for the developing brain 681037
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.49molecular biology in Saccharomyces cerevisiae separase it is shown that separase is implicated in a second non-proteolytic pathway: separsae is essential for the activation of Cdc14 phosphatase and thus a broad programme of late mitotic events culminating in mitotic exit and cell division 682065
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.49molecular biology separase is identified as a key cell cycle component that is required for degranulation 679433
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.49molecular biology separse is not only required for chromosome segregation but also for meiotic exit 682065
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.49molecular biology the results indicate that inhibitory phosphorylation of separase plays a critical role in the maintenance of sister chromatid cohesion and genome stability in proliferating postmigratory primordial germ cells 682481
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.49molecular biology the results show that a fraction of arm cohesin is protected by Sgo1, which prevents cohesin from being removed by the prophase pathway, and that separase is partly activated in nocodazole-arrested cells and removes the arm cohesion protected by Sgo1 681015
Results 1 - 9 of 9