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3.2.1.B43
medicine
an LC-MS/MS assay utilising keratan sulphate disaccharides derived from keratanase-II digestion provides a sensitive and specific means for quantitation of urinary keratan sulfate, a screening biomarker for Morquio A. The C-terminally truncated, recombinant keratanase-II meets all performance requirements and can be produced in a rapid and reproducible manner
750338
3.2.1.B43
medicine
sulfated type 2 carbohydrate chains are known tumor-associated carbohydrate antigens (TACAs). The enzyme efficiently catalyzes the transglycosylation reaction of the sulfated Lewis X (Galbeta(1->4)[Fucalpha(1->3)]GlcNAc(6-OSO3-)) oxazoline derivative, thereby giving the su-Lex dimer as the main product in good yields
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750313
3.2.1.B43
molecular biology
truncated forms of keratanase II exhibit activity and excellent storage and thermal stability making these useful tools for glycobiology research
750715
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