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EC Number Application Commentary Reference
Show all pathways known for 2.7.1.5Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.5synthesis production of L-Rhamnulose (6-deoxy-L-arabino-2-hexulose) and L-fuculose (6-deoxy-L-lyxo-2-hexulose) from L-rhamnose and L-fucose. First, isomerization of L-rhamnose to L-rhamnulose, or L-fucose to L-fuculose is combined with a targeted phosphorylation reaction catalyzed by L-rhamnulose kinase (RhaB). The by-products (ATP and ADP) are selectively removed by silver nitrate precipitation method. In the second step, the phosphate group is hydrolyzed to produce L-rhamnulose or L-fuculose with purity exceeding 99% in more than 80% yield 737832
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