EC Number |
Application |
Reference |
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2.5.1.22 | agriculture |
OsSPMS1 knockout mutant show an increase in grain yield per plant in a high-yield variety, Suken118 suggesting that OsSPMS1 is an important target for yield enhancement in rice |
759983 |
2.5.1.22 | medicine |
enzyme null mutant, lack of spermine increases sensitivity of cells to anti-tumor agents |
489877 |
2.5.1.22 | medicine |
mutation p.G56S in the N-terminal region of spermine synthase greatly reduces spermine synthase activity and leads to severe epilepsy and cognitive impairment related to Snyder-Robinson X-linked recessive mental retardation syndrome |
688299 |
2.5.1.22 | medicine |
Snyder-Robinson syndrome (SRS) mutations drastically reduce spermine synthase activity and cause mild-to-moderate mental retardation, and may lead to a variety of other characteristics including a marfanoid habitus, skeletal defects, osteoporosis, and facial asymmetry, as well as hypotonia and movement disorders |
708060 |
2.5.1.22 | medicine |
specific and marked decrease in spermine after diet containing N-(3-aminopropyl)cyclohexylamine |
489876 |