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EC Number Application Commentary Reference
Show all pathways known for 2.3.1.24Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.24analysis fluorescent CERS assay with quantification using thin-layer chromatography or high-performance liquid chromatography 757588
Show all pathways known for 2.3.1.24Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.24diagnostics important role for the CerS genes in breast cancer etiology or diagnosis, overview 752644
Show all pathways known for 2.3.1.24Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.24medicine isoform CerS6 is specifically upregulated in experimental alcoholic steatosis in vivo and in vitro 756688
Show all pathways known for 2.3.1.24Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.24medicine isoform CerS6 is specifically upregulated in experimental alcoholic steatosis in vivo and in vitro. In vivo ceramide reduction by inhibition of de novo ceramide synthesis reduces PLIN2 and hepatic steatosis in alcohol-fed mice, and improves glucose homeostasis in control and Etoh mice, but only de novo synthesis inhibition. Inhibition of ceramide synthesis during alcohol feeding has minimal effect on body composition, food intake, and energy expenditure 756688
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