EC Number |
Application |
Reference |
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2.2.1.2 | industry |
production of abundant intermediates for industrially erythritol production |
-, 704746 |
2.2.1.2 | medicine |
clinical presentation and laboratory findings of a new patient with TALDO deficiency: a two-year-old Arabic boy presented with neonatal onset of anemia and thrombocytopenia, tubulopathy, and rickets and is subsequently found to have cirrhosis and deafness |
689023 |
2.2.1.2 | medicine |
male mice lacking transaldolase are sterile because of defective forward motility of spermatozoa. Transaldolase -/- spermatozoa show loss of transmembrane potential and mitochondrial membrane integrity. Lack of enzyme influencies structure and function of mitochondria without compromising the nucleus and DNA integrity. Stimulation of de novo glutathione synthesis by oral N-acetyl-cysteine normalizes the low fertility rates of transaldolase +/- males without affecting the sterility of transaldolase -/- mice |
676818 |
2.2.1.2 | medicine |
the results provide preliminary evidence that genetic polymorphisms in TALDO1 are associated with squamous cell carcinoma of the head and neck |
685916 |
2.2.1.2 | medicine |
transaldolase shows a high mucin binding capacity. When exposed on the cell surface of Bifidobacterium bifidum, enzyme may act as an important colonization factor favoring its establishment in the gut. A recombinant Lactococcus lactis strain, engineered to secrete transaldolase, displays a mucin-binding level more than three times higher than the strain not producing the transaldolase |
-, 718647 |
2.2.1.2 | medicine |
transaldolase-deficient patients have significantly increased urinary sedoheptulose and sedoheptulose 7-phosphate, associated with subtle elevations of mannoheptulose, sedoheptitol and perseitol. The development of a liquid chromatography-tandem mass spectrometry method for quantitation of the seven-carbon carbohydrates biomarkers in urine is shown |
688180 |
2.2.1.2 | molecular biology |
TAL deficiency is shown as a modulator of mitochondrial homoeostasis, Ca2+ fluxing and apoptosis |
685010 |
2.2.1.2 | synthesis |
improvement of xylose-to-ethanol bioconversion by mutation Q263R, mutantion leads to 5fold increase in activity and increases ethanol production by 36% and 100% as measured by volumetric production rate and specific production rate, respectively |
718464 |
2.2.1.2 | synthesis |
mutation F178Y/R181E is based on mutant F178Y, which is able to use dihydroxyacetone as donor in aldol reactions. Mutant F178Y/R181E exhibits an at least fivefold increase in affinity towards glyceraldehyde and can use D- and L-glyceraldehyde as acceptor substrates, resulting in preparative synthesis of D-fructose, D-xylulose and L-sorbose when dihydroxyacetone is used as donor. Mutant enzyme does not show transaldolase activity |
719286 |
2.2.1.2 | synthesis |
overexpression of enzyme in Escherichia coli harboring poly-beta-hydroxybutyrate operon phbCAB leads to increase in poly-beta-hydroxybutyrate from 28.2% to 52.3% |
674954 |