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EC Number	Application	Commentary	Reference
2.1.1.382	synthesis	the demethylation by VdmB transforms a variety of aryl methyl ethers with two functional methoxy moieties either in 1,2-position or in 1,3-position. Biocatalytic reactions enable the regioselective monodemethylation of substituted 3,4-dimethoxy phenol as well as the monodemethylation of 1,3,5-trimethoxybenzene. The VdmB is also applied for the regioselective demethylation of natural compounds such as papaverine and rac-yatein. Best results are obtained in presence of orcinol as final methyl acceptor	763782

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Release 2023.1 (January 2023)