EC Number   |
Application |
Reference |
|---|
    1.4.3.14 | agriculture |
the enzyme inhibits the growth of highly infectious bacterium Erwinia amylovora (causative agent of fire blight) |
-, 764390 |
| 1.4.3.14 | agriculture |
the enzyme is active towards pathogenic microorganisms, fungi, and nematodes. It exhibits inhibitory effect towards extremely hazardous Acidovorax citrulli bacterium (that causes seedling blight and bacterial fruit blotch of cucurbits) |
-, 764391 |
| 1.4.3.14 | analysis |
L-lysine-alpha-oxidase is immobilised by co-crosslinking onto the surface of a Pt electrode. The resulting amperometric biosensor is able to analyse L-lysine. The immobilised enzymes and amperometric biosensor can be used for substrate analysis and as a convenient tool for enzyme kinetic studies |
764336 |
| 1.4.3.14 | medicine |
- |
391747, 391748 |
| 1.4.3.14 | medicine |
antitumor activity |
-, 391744, 391745, 391746, 391750, 391752, 391753 |
| 1.4.3.14 | medicine |
suppresses efficiently genital herpes simplex virus type II (HSV-2) infection in guinea pig, showing the best results after combined treatment with enzyme gel and intramuscular injection on day 5 postinfection |
-, 391753 |
| 1.4.3.14 | medicine |
the enzyme is an anticancer agent for the treatment of solid tumors in vivo |
741611 |
| 1.4.3.14 | medicine |
the enzyme may be used to reduce levels of L-Lys and polyamines in the brain. The enzyme enetrates into the brain and is retained there for up to 48 h after intravenous injection. The most significant impact of the enzyme is towards amino acids, which are directly exposed to its action (L-Lys, L-Orn, L-Arg). In addition, the enzyme significantly affects the redistribution of amino acids directly associated with the tricarboxylic acid cycle (L-Asp and l-Glu). The depletion of L-Orn, the precursor of polyamines, leads to a significant and long-term decrease in the concentration of polyamines, which are responsible for regulation of many processes including cell proliferation |
-, 765511 |
| 1.4.3.14 | medicine |
the enzyme severely inhibits growth of cancer cells but shows relatively low cytotoxicity fo normal cells |
-, 742804 |
| 1.4.3.14 | nutrition |
the optical enzyme sensor system with immobilized LyOx membrane can be used for rapid determination of L-Lys in a real food sample |
684396 |
