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EC Number Application Commentary Reference
Show all pathways known for 1.1.1.88Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.88medicine in endotoxemic mice, leukocyte infiltration in the liver is significantly elevated. Simvastatin significantly reduces endotoxin-induced hepatocellular damage and apoptosis. Hepatic accumulation of leukocytes is attenuated by simvastatin. Co-administration of mevalonate abolishes the protective effects of simvastatin on endotoxin-provoked increases in serum alanine transferase and serum alanine transferase as well as leukocyte recruitment 712670
Show all pathways known for 1.1.1.88Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.88medicine pterygium has an altered metabolism of cholesterol, namely increased LDL-R and HMG-CoA-R mRNAs. Both genes may play important roles in the pathogenesis of pterygium 712196
Show all pathways known for 1.1.1.88Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.88medicine target enzyme for chemotherapy of hypercholesterolemias 287506
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