Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Application

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 4 of 4
EC Number Application Commentary Reference
Show all pathways known for 1.1.1.274Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.274biotechnology enzyme is a target for the construction of a NADH-utilizing mutant strain in the industrial production of vitamin C 657308
Show all pathways known for 1.1.1.274Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.274synthesis enzymatic production of the vitamin C precursor 2-keto-L-gulonate (2-KLG) from 2,5-diketo-D-gluconate (2,5-DKG) by coupling 2,5-diketo-D-gluconic acid reductase via its coenzyme to glucose dehydrogenase. The bienzymatic process shows complicated inhibition patterns caused by reaction products, NADP+ and NADPH. The key parameters for a fast and efficient conversion are the NADP(H) concentration, the volumetric activity of 2,5-DKG reductase, the ratio of synthetic enzyme activity to regenerate enzyme activity and the glucono-1,5-lactone concentration. By modeling the space-time yield of the process is nearly doubled and the coenzyme concentration reduced threefold 740008
Show all pathways known for 1.1.1.274Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.274synthesis enzyme can be used in the industrial production of vitamin C 657308
Show all pathways known for 1.1.1.274Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.274synthesis enzyme may be useful for the synthesis of the ascorbate precursor 2-keto-L-gulonate 440306
Results 1 - 4 of 4