EC Number |
Natural Substrates |
---|
6.5.1.4 | ATP + RNA 3'-terminal-phosphate |
the enzyme could be involved in the maintenance of cyclic ends in tRNA splicing intermediates or in the cyclization of the 3' end of U6 sbRNA |
6.5.1.4 | ATP + RNA 3'-terminal-phosphate |
role in RNA processing |
6.5.1.4 | ATP + [RNA 3'-phosphate cyclase]-L-histidine |
- |
6.5.1.4 | ATP + [RNA]-3'-(3'-phospho-ribonucleoside) |
- |
6.5.1.4 | more |
it was suggested that the enzyme could be responsible for the generation of the 2',3'-cyclic termini required for ligation of RNA by eukaryotic ligases and, consequently, be involved in tRNA slicing. It was found, however, that the slicing endonucleases responsible for the excision of introns from tRNA precursors in yeast and Xenopus sp. directly produce RNA molecules with cyclic phosphate ends |
6.5.1.4 | more |
nonessential as demonstrated by knockout experiments |
6.5.1.4 | more |
precise function is not known, may be responsible for generating or regenerating cyclic phosphate RNA ends required by RNA ligases |
6.5.1.4 | [RNA 3'-phosphate cyclase]-Ntau-(5'-adenylyl)-L-histidine + [RNA]-3'-(3'-phospho-ribonucleoside) |
- |
6.5.1.4 | [RNA]-3'-ribonucleoside-3'-(5'-diphosphoadenosine) |
- |