EC Number   |
Natural Substrates |
|---|
    6.2.1.2 | ATP + a medium chain fatty acid or an aromatic acid or an arylacetic acid + CoA |
the enzyme catalyzes the first reaction of glycine conjugation, which is an important route of detoxification of many xenobiotic and endogenous carboxylic acids |
| 6.2.1.2 | ATP + L-(+)-3-hydroxybutyrate + CoA |
enzyme reesterifies CoA and L-(+)-3-hydroxybutyrate. It is required for the production of L-(+)-3-hydroxybutyrate in rat liver |
| 6.2.1.2 | ATP + phenylacetate + CoA |
enzymatic activation of phenylacetic acid to phenylacetyl-CoA is an important step in the biosynthesis of the beta-lactam antibiotic penicillin G by the fungus Penicillium chrysogenum, CoA esters of PAA and phenoxyacetic acid act as acyl donor in the exchange of the aminoadipyl side chain of isopenicillin N to produce penicillin G or penicillin V |
| 6.2.1.2 | more |
major enzyme for glycine conjugation of benzoic acids with electron-donating groups in bovine liver mitochondria |
| 6.2.1.2 | more |
the enzyme catalyzes the first reaction of glycine conjugation |
| 6.2.1.2 | more |
the enzyme is involved in the metabolism of fatty acid during mycobacterial survival in macrophages |
| 6.2.1.2 | more |
the enzyme is responsible for glycine conjugation |
