EC Number |
Natural Substrates |
---|
6.1.1.4 | ATP + 2-butynylalanine + tRNALeu |
aminoacylation by mutant T252Y |
6.1.1.4 | ATP + allylglycine + tRNALeu |
aminoacylation by mutant T252Y |
6.1.1.4 | ATP + homoallylglycine + tRNALeu |
aminoacylation by mutant T252Y |
6.1.1.4 | ATP + homopropargylglycine + tRNALeu |
aminoacylation by mutant T252Y |
6.1.1.4 | ATP + L-leucine + tRNAIle |
- |
6.1.1.4 | ATP + L-leucine + tRNALeu |
- |
6.1.1.4 | ATP + L-leucine + tRNALeu |
the reaction catalyzed by the enzyme plays an important role in the transport of aminoacylated tRNAs from the nucleus to the cytoplasm |
6.1.1.4 | ATP + L-leucine + tRNALeu |
human cytosolic leucyl-tRNA synthetase is one component of a macromolecular aminoacyl-tRNA synthetase complex. The C-terminal peptide of hcLeuRS is critical for the interaction with hcArgRS and the interaction in the multi-tRNA synthetase complex |
6.1.1.4 | ATP + L-leucine + tRNALeu |
a complex between prolyl-tRNA synthetase, ProRS, and LeuRS in Methanothermobacter thermautotrophicus enhances tRNAPro aminoacylation, overview |
6.1.1.4 | ATP + L-leucine + tRNALeu |
possibly the yeast mitochondria have evolved to tolerate lower levels of fidelity in protein synthesis or have developed alternate mechanisms to enhance discrimination of leucine from non-cognate amino acids that can be misactivated by leucyl-tRNA synthetase |