EC Number |
Natural Substrates |
---|
6.1.1.10 | ATP + azidonorleucine + tRNAMet |
activity of mutant L13G, overview |
6.1.1.10 | ATP + L-homocysteine + tRNAMet |
edition and aminoacylation by cytoplasmic and mitochondrial isozyme |
6.1.1.10 | ATP + L-methionine + tRNAMet |
- |
6.1.1.10 | ATP + L-methionine + tRNAMet |
initiator and elongation tRNAMet, cytoplasmic and mitochondrial isozyme |
6.1.1.10 | ATP + L-methionine + tRNAMet |
L-methionine and methionine analogue substrates are incorporated in proteins, overview |
6.1.1.10 | ATP + L-methionine + tRNAMet |
protein biosynthesis in archaea is initiated with methionine not with formylmethionine |
6.1.1.10 | ATP + L-methionine + tRNAMet |
the nucleolar located enzyme is related to rRNA synthesis, the cytoplasmic enzyme is involved in protein biosynthesis |
6.1.1.10 | ATP + L-methionine + tRNAMet |
essentiality of the metS1, nonessentiality of the metS2 for vegetative growth |
6.1.1.10 | ATP + L-methionine + tRNAMet |
the MetRS specificity for methionine and conformity with the identity rules for tRNAMet for archea/eukarya, anticodon binding site, overview |
6.1.1.10 | ATP + L-methionine + tRNAMet |
MetRS specifically binds tRNAMet and catalyzes the synthesis of methionyl-tRNAMet. The C-terminal appended domain causes a slow release of aminoacyl-tRNA and establishes a limiting step in the global aminoacylation reaction |