EC Number   |
Natural Substrates |
|---|
    6.1.1.1 | ATP + 3-(2-naphthyl)alanine + tRNATyr |
activity of a natural mutant enzyme, NpAla TyrRS activity |
| 6.1.1.1 | ATP + 4-acetylphenylalanine + tRNATyr |
activity of a natural mutant enzyme |
| 6.1.1.1 | ATP + 4-bromophenylalanine + tRNATyr |
activity of a natural mutant enzyme, p-BrPhe TyrRS activity |
| 6.1.1.1 | ATP + L-beta-(5-hydroxy-2-pyridyl)-alanine + tRNATyr |
L-beta-(5-hydroxy-2-pyridyl)-alanine i.e. azatyrosine, mutant F130S shows 17fold higher activity in vivo than the wild-type enzyme |
| 6.1.1.1 | ATP + L-tyrosine + tRNATyr |
- |
| 6.1.1.1 | ATP + L-tyrosine + tRNATyr |
the TyrRS specificity for tyrosine and conformity with the identity rules for tRNATyr for archea/eukarya, anticodon binding site, overview |
| 6.1.1.1 | ATP + L-tyrosine + tRNATyr |
wild-type activity |
| 6.1.1.1 | ATP + tyrosine + tRNATyr |
- |
| 6.1.1.1 | ATP + tyrosine + tRNATyr |
enzyme plays a key role in protein biosynthesis |
| 6.1.1.1 | more |
the enzyme's C-terminal domain, an EMAP II-like protein, is active in angiogenesis pathways and stimulates immune cells, when cleaved off the enzyme, it stimulates blood vessel development |
