EC Number   |
Natural Substrates |
|---|
    5.1.1.18 | L-aspartate |
- |
| 5.1.1.18 | L-serine |
- |
| 5.1.1.18 | L-serine |
D-serine is a coagonist with glutamate at NMDA receptors, postsynaptic stimulation of nitric-oxide formation feeds back to presynaptic cells to S-nitrosylate SR and decrease D-serine availability to postsynaptic NMDA receptors, enzyme regulation, mechanism, overview |
| 5.1.1.18 | L-serine |
D-serine is an N-methyl-d-aspartate receptor co-agonist, synthesized by serine racemase and degraded by d-amino acid oxidase |
| 5.1.1.18 | L-serine |
D-serine, an endogenous co-agonist of N-methyl-D-aspartate receptors in vertebrate retina, modulates glutamate sensitivity of retinal neurons, overview |
| 5.1.1.18 | L-serine |
developmental regulation of enzyme expression in neuronal ganglion cells of the retina, overview, D-serine is the endogenous ligand for the glycine modulatory binding site of the NMDA receptor |
| 5.1.1.18 | L-serine |
the astrocytic enzyme synthesizes the N-methyl-D-aspartate receptor coagonist D-serine, and is involved in development of schizophrenia and glutamatergic dysfunction, astrocytes may play a direct role in N-methyl-D-aspartate receptor dysfunction in schizophrenia, overview |
| 5.1.1.18 | L-serine |
D-serine is stored primarily within astrocytes ensheathing neuronal synapses containing NMDA receptors, model of D-serine signalling in the brain, overview |
| 5.1.1.18 | L-serine |
mechanisms regulating D-serine production by the enzyme serine racemase via translocation from cytosol to membranes, overview |
| 5.1.1.18 | L-threonine |
- |
