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EC Number
Natural Substrates
Commentary (Nat. Sub.)
4.1.3.44
N1-methylguanine37 in tRNAPhe + pyruvate + S-adenosyl-L-methionine
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4.1.3.44
N1-methylguanine37 in tRNAPhe + pyruvate + S-adenosyl-L-methionine
enzyme catalyzes the condensation of N-methylguanosine with two carbon atoms from pyruvate to form 4-demethylwyosine, which is a common intermediate in the biosynthesis of all of the hypermodified RNA bases related to wybutosine. C2 and C3 of pyruvate are incorporated while C1 is not
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