EC Number |
Natural Substrates |
---|
4.1.1.49 | ADP + phosphoenolpyruvate + CO2 |
- |
4.1.1.49 | ADP + phosphoenolpyruvate + CO2 |
synthesis of oxaloacetate is a key step in the formation of four-carbon compounds, such as malate, fumarate, and succinate |
4.1.1.49 | ADP + phosphoenolpyruvate + CO2 |
in contrast to its normal role in gluconeogenesis, PEP carboxykinase can operate in the reverse direction from phosphoenolpyruvate to oxaloacetate, upon knockout of pyruvate kinase in a riboflavin-producing Bacillus subtilis strain and in wild-type 168 |
4.1.1.49 | ADP + phosphoenolpyruvate + CO2 |
the enzyme is responsible for the CO2 fixation |
4.1.1.49 | ADP + phosphoenolpyruvate + CO2 |
catabolic CO2-fixing enzyme, important role in succinate formation |
4.1.1.49 | ATP + oxaloacetate |
- |
4.1.1.49 | ATP + oxaloacetate |
acts in the metabolic pathways at the intersection of the glycolysis, the gluconeogenesis and the Krebs cycle, enzyme activity increases when cells are submitted to hypothermic stress |
4.1.1.49 | ATP + oxaloacetate |
carbon and nitrogen metabolism |
4.1.1.49 | ATP + oxaloacetate |
critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates towards gluconeogenesis |
4.1.1.49 | ATP + oxaloacetate |
first commmitted step of gluconeogenesis |