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EC Number
Natural Substrates
Commentary (Nat. Sub.)
3.4.23.3
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progastricsin is responsible for the autoproteolysis of seminal fluid proteins under acidic conditions. This suggests that the function of the enzyme is to degrade seminal fluid proteins deposited in the vagina, this in turn may decrease the antigenic load in the vagina and prevent immuno-infertility
3.4.23.3
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transcriptional regulation of the pepsinogen C gene, presence of a DNA-binding protein that specifically binds to the promoter region of the rat pepsinogen C gene
3.4.23.3
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pepsinogen C expression by human mammary epithelium may be involved in the development of breast diseases
3.4.23.3
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the enzyme shows very high gastric antibacterial efficiency against Helicobacter pylori at pH 2.0
3.4.23.3
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role of this gastric digestive enzyme in the regulation of food intake
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