EC Number |
Natural Substrates |
---|
3.4.22.39 | core polypeptide pVI + H2O |
- |
3.4.22.39 | core polypeptide pVI + H2O |
the enzyme cleaves DNA-bound pVI twice, once at its N terminus and then at its C terminus. Cleavage at the C terminus liberates pVIc, the 11-amino acid peptide cofactor |
3.4.22.39 | more |
the enzyme can function as deubiquitinating enzyme in vitro and in vivo. The protein deubiquitination can be as efficient as proteolytic processing of viral proteins |
3.4.22.39 | more |
required for the synthesis of infectious virus and is a target for antiviral therapy |
3.4.22.39 | preterminal proteins |
pVI, pVII, pVIII, IIIa, 11K |