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Results 1 - 5 of 5

EC Number	Natural Substrates	Commentary (Nat. Sub.)
3.4.16.2	alpha-melanocyte-stimulating hormone + H2O	evidence is provided that in mice, PRCP degrades alpha-melanocyte-stimulating hormone to an inactive form that is unable to inhibit food intake
3.4.16.2	alpha-melanocyte-stimulating hormone + H2O	using recombinant PRCP it is shown that PRCP removes the C-terminal amino acid of alpha-melanocyte-stimulating hormone1-13, producing alpha-melanocyte-stimulating hormone1-12, which is not neuroactive
3.4.16.2	more	overexpression of prolylcarboxypeptidase enhances plasma prekallikrein activation on Chinese hamster ovary cells
3.4.16.2	more	the enzyme is a plasma prekallikrein activator
3.4.16.2	YPRPIHPA + H2O	using a peptidomic approach a single peptide YPRPIHPA is identified as a novel substrate for PRCP in human cerebrospinal fluid. The peptide YPRPIHPA is from the extracellular portion of human endothelin B receptor like protein 2

Results 1 - 5 of 5

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Release 2023.1 (January 2023)