EC Number   |
Natural Substrates |
|---|
   3.4.11.9 | bradykinin + H2O |
potential natural substrate, efficiently hydrolyzed by PfAPP |
| 3.4.11.9 | bradykinin + H2O |
enzyme activity in plasma of humans with previous angio-oedema, a rare but potentially life-threatening side-effect of angiotensin-converting enzyme inhibitor treatment, is low compared to humans without this sensitivity and might be a predisposing factor for development of angio-oedema |
| 3.4.11.9 | bradykinin + H2O |
the enzyme contributes to the degradation of bradykinin in human skin, especially in case of angiotensin-converting enzyme inhibition |
| 3.4.11.9 | FPHFD + H2O |
globin pentapeptide sequence, potential natural substrate, efficiently hydrolyzed by PfAPP |
| 3.4.11.9 | more |
enzyme may be important for the modulation of the biological activity of neuropeptides |
| 3.4.11.9 | more |
the enzyme is involved in the pulmonary inactivation of circulating bradykinin |
| 3.4.11.9 | more |
the enzyme accounts for virtually all of the pulmonary inactivation of bradykinin injected in vitro |
| 3.4.11.9 | more |
the enzyme probably plays an important role in conjunction with other intestinal prolyl peptidases in the digestion of proline containing peptides and proteins |
| 3.4.11.9 | more |
aminopeptidase P appears to be an important enzyme for debittering of casein-derived peptides |
| 3.4.11.9 | more |
the enzyme is involved in degradation of peptide intermediates |
