EC Number |
Natural Substrates |
---|
3.3.2.6 | (7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate + H2O |
- |
3.3.2.6 | (7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate + H2O |
substrate for epoxide hydrolase activity |
3.3.2.6 | (7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate + H2O |
substrate for the epoxide hydrolase reaction, in addition LTA4H shows a peptidase activity |
3.3.2.6 | leukotriene A4 + H2O |
- |
3.3.2.6 | leukotriene A4 + H2O |
one of the physiologically important processes in the arachidonic acid biosynthetic pathway, leukotriene B4 is a proinflammatory mediator which stimulates adhesion of circulating neutrophils to vascular endothelium and directs their migration towards sites of inflammation |
3.3.2.6 | leukotriene A4 + H2O |
central enzyme in leukotriene B4 formation, it is likely to be involved in transcellular leukotriene formation |
3.3.2.6 | leukotriene A4 + H2O |
biosynthesis of leukotriene B4 |
3.3.2.6 | leukotriene A4 + H2O |
leukotriene A4 hydrolase catalyzes the final step in the synthesis of leukotriene B4, a potent chemoattractant and proinflammatory eicosanoid |
3.3.2.6 | leukotriene A4 + H2O |
leukotriene A4 hydrolase catalyzes the final step in the synthesis of leukotriene B4, a potent chemoattractant and proinflammatory eicosanoid. LTB4 functions as a macrophage chemoattractant in the zebrafish, injection into the hindbrain ventricle of wild-type arvae induces rapid recruitment of macrophages |
3.3.2.6 | more |
possible proteolytic function of the enzyme may be limited to the extracellular space |