EC Number |
Natural Substrates |
---|
3.2.2.22 | 23S rRNA + H2O |
- |
3.2.2.22 | 28S rRNA + H2O |
- |
3.2.2.22 | 28S rRNA + H2O |
inactivation of protein translation in targeted cells, e.g. bacterial cells, where the toxin is transported into the cytosol |
3.2.2.22 | 28S rRNA + H2O |
saporin is a type I ribosome-inactivating protein with N-glycosidase activity. It removes adenine residues from the 28S ribosomal RNA resulting in inhibition of protein synthesis |
3.2.2.22 | 28S rRNA + H2O |
depurination at A4324, removal of adenine from rRNA, inactivating ribosomal function in translation |
3.2.2.22 | 28S rRNA + H2O |
depurination or 28S rRNA, removal of adenine from rRNA, inactivating ribosomal function in translation |
3.2.2.22 | 28S rRNA + H2O |
depurination of a specific adenine in 28S rRNA |
3.2.2.22 | adenosine in rRNA + H2O |
rRNA is depurinated thus producing inactive ribosomes and inhibition protein synthesis probably due to the lack of the interaction between depurinated ribosomes and elongation factor 2 |
3.2.2.22 | brome mosaic virus RNA + H2O |
depurination of the viral RNA, anti-viral activity of PAP by inhibition of accumulation of viral RNA and viral proliferation in barley protoplasts, overview |
3.2.2.22 | large rRNA + H2O |
inhibition of translation and protein synthesis, cytotoxic |