EC Number |
Natural Substrates |
---|
3.1.4.3 | 1,2-diacyl-sn-glycero-3-phosphatide + H2O |
- |
3.1.4.3 | glycan-phosphatidylinositol + H2O |
- |
3.1.4.3 | lysophosphatidylcholine |
- |
3.1.4.3 | membrane form variant surface glycoproteins + H2O |
- |
3.1.4.3 | more |
enzyme induces cell cycle progression, overexpression of enzyme induces overexpression of cyclin D3 |
3.1.4.3 | more |
enzyme activity is necessary for PLC-induced inflammation |
3.1.4.3 | more |
hemolytic fractions from strain ATCC 19660 cause paralysis, death, dermonecrosis, footpad swelling, and vascular permeability in mice. The toxicity is directly associated with enzymatic activity |
3.1.4.3 | more |
homoserine lactone-mediated quorum sensing regulates the expression of PA0026, which encodes PlcB. PlcB is required for directed twitching motility up a gradient of certain kinds of phospholipids |
3.1.4.3 | more |
phospholipase C causes platelet aggregation in a concentration-dependent manner |
3.1.4.3 | more |
phospholipase C plays a role in pathogenesis of infections by Pseudomonas aeruginosa |