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Results 1 - 8 of 8
EC Number Natural Substrates Commentary (Nat. Sub.)
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.63'-AMP processing of exogenously available 3'-nucleotides into a form suitable for transport across the surface membrane of the parasite, which is incapable of purine biosynthesis de novo
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.63'-AMP + H2O -
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.6a 3'-ribonucleotide + H2O -
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.6more the enzyme is involved in salvage of host-derived purines, which are essential for the survival of the parasite
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.6more the enzyme is involved in the salvage of preformed purines via the hydrolysis of either 3'-nucleotides or nucleic acids
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.6more the enzyme must play a critical role in purine salvage of the human pathogen
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.6more the enzyme plays a critical role in purine salvage pathway during the rapid multiplicative expansion of the parasite population within its insect vector. Starvation of the parasite for purines results in the significant up-regulation of both the 3'-nucleotidase/nuclease mRNA and enzyme activity in promastigotes, but not in amastigotes
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.6more the enzyme cleaves RNA and heat-denatured DNA endonucleolytically producing 5'-mononucleotides and shows 3'-nucleotidase activity
Results 1 - 8 of 8