EC Number   |
Natural Substrates |
|---|
   3.1.3.36 | 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + H2O |
- |
| 3.1.3.36 | 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O |
- |
| 3.1.3.36 | 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O |
preferred substrate |
| 3.1.3.36 | 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O |
synaptojanin-1 regulates of turnover of a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate pool involved Ca2+ signalling and in clathrin and actin dynamics at the cell surface, SJ-1 attenuates the oscillations of Ca2+ induced by ATP and the catalytic domain of its 5-Pase domain mimicking the effect, overview |
| 3.1.3.36 | 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O |
the enzyme is involved in regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate levels in stem |
| 3.1.3.36 | 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O |
the enzyme is involved in regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate levels, an important second messenger in signalling pathways, e.g. MAP kinase activation, enzyme regulation by effectors TAX4 and IRS4, overview |
| 3.1.3.36 | 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O |
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate is required for formation, polarization, and elongation of spermatid cysts, overview |
| 3.1.3.36 | 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O |
the voltage-sensitive phosphoinositide phosphatase Ci-VSP, a membrane-resident PI(4,5) P2-5-phosphatase, removes phosphatidylinositol-4,5-bisphosphate from the plasma membrane |
| 3.1.3.36 | more |
the diabetic state does not affect enzyme activity |
| 3.1.3.36 | more |
acetylcholine increases activity |
