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EC Number
Natural Substrates
Commentary (Nat. Sub.)
3.1.1.111
a 1-acyl-2-lyso-phosphatidylserine + H2O
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3.1.1.111
a phosphatidylserine + H2O
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3.1.1.111
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an alternative splicing 376-amino acid product lacks two-thirds of the C-terminal domain of PS-PLA1 hydrolyzes exclusively lyso-phosphatidylserine but not phosphatidylserine appreciably. Phosphatidylcholine, phosphatidylethanolamine, phosphatidic acid, and their lyso derivatives are not hydrolyzed at all by the variant
3.1.1.111
phosphatidylserine + H2O
PS-PLA1 stimulates histamine release from peritoneal mast cells through production of 2-acyl-1-glycerophosphoserine
3.1.1.111
phosphatidylserine + H2O
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