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EC Number
Natural Substrates
Commentary (Nat. Sub.)
2.7.7.86
ATP + GTP
cyclic 3',5'-AMP-GMP is a signalling molecule in mammalian cells that triggers the production of type I interferons and other cytokines
2.7.7.86
ATP + GTP
-
2.7.7.86
ATP + GTP
overall reaction
2.7.7.86
ATP + GTP
over 78% conversion within 40 min
2.7.7.86
more
interaction of cGAS and viral DNA sensor IFI16, the pyrin domain of IFI16 mediates the interaction with ND10 bodies and enzyme cGAS
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