EC Number |
Natural Substrates |
---|
2.7.6.1 | ATP + D-ribose 5-phosphate |
- |
2.7.6.1 | ATP + D-ribose 5-phosphate |
the product phosphoribosyldiphosphate is required for the biosynthesis of purine, pyrimidine and pyridine nucleotides, L-histidine and L-tryptophan |
2.7.6.1 | ATP + D-ribose 5-phosphate |
the enzymatic activity of PRS is regulated by both the activator phosphate and the inhibitor ADP competing for binding at a common allosteric regulatory site |
2.7.6.1 | D-ribose 5-phosphate + ATP |
PRPP (phosphoribosylpyrophosphate) synthetases are a family of enzymes that catalyse the synthesis of PRPP from ATP and R5P (ribose 5-phosphate) by transferring the beta, gamma-diphosphoryl moiety of ATP to the C1-hydroxy group of R5P. |
2.7.6.1 | D-ribose 5-phosphate + ATP |
biosynthesis of purines and pyrimidines |
2.7.6.1 | more |
the phosphoribosyl pyrophosphate synthetase enzyme critical for nucleotide biosynthesis |
2.7.6.1 | ribose-5-phosphate + ATP |
first step in purine metabolic pathway |